Science

The solution to modern appetite challenges

Helping people navigate our calorie environment.

Our appetites evolved for a world of calorie scarcity. We do not realize our stomachs are full until about 40 minutes after eating. 

This is how long it takes for the GLP-1 signals to be released from digestion interaction and reach the brain. This was fine in a world before the abundance of calorie-dense foods. It is possible to consume many more calories than nature ever intended before knowing we have had enough.

Calocurb closes the loop.

Taking Calocurb before a meal primes your brain to feel it has already eaten some food. You can enjoy the taste, feeling and satiety of eating but can easily exert better control over portion size and snacking - as you feel full faster. 

Perhaps never before has weight management involved feeling full and satisfied. We envision a world where having two Calocurbs before a meal is as common as having a coffee to feel more alert or eating whole foods to snack sensibly.

We advocate for eating well and living a balanced, healthy life.

The solution to modern appetite challenges

Clinical trials

Calocurb harnesses a natural response in the body using 100% plant-based ingredients and patented delayed-release capsule technology. This blend of old science and new was developed by Plant & Food Research (PFR), New Zealand’s largest Crown Research Institute.

PFR screened over 900 plants to find the best all-natural appetite suppressant: a New Zealand grown bitter hops flower extract called Amarasate® (Am-ar-eh-sate).

After 14 years of research and more than $30 million dollars in funding, Amarasate® has been clinically shown to regulate eating behavior by reducing appetite, cravings, and caloric intake in just one hour.

Three clinical trials in both men and women have shown:

- 30% reduction in hunger
New Zealand Bitter Hops Extract Reduces Hunger During a 24h Water Only Fast. 
Nutrients 2019, 11 (11), 2754

- 40% reduction in cravings
Gastrointestinal Delivery of Bitter Hops Extract Reduces Appetite and Food Cravings in Healthy Adult Women Undergoing Acute Fasting.
Obesity Pillars 2024, 100117

- 18% reduction in calories consumed
An Extract of Hops (Humulus Lupulus L.) Moderates Gut Peptide Hormone Secretion and Reduces Energy Intake in Healthy-Weight Men: A Randomized, Cross Over Clinical Trial.
The American Journal of Clinical Nutrition 2022, 115(3), 925-940

Clinical trials

Ingredients

Three ingredients. That's it.

Calocurb's active ingredient is Amarasate®, an extract from hops only grown in the South Island of New Zealand.

Amarasate® works by stimulating the gastric tastebuds to release a natural blend of gastric peptides GLP-1, CCK, and PYY. This triggers the 'bitter break' that helps the body effectively manage appetite, overeating, cravings, and hunger.

In a GMP (Good Manufacturing Practice) credited facility, Amarasate® is gently blended with Calocurb's other two ingredients, rosemary leaf extract (a natural preservative) and a Non-GMO, glycophosphate-free canola oil (a stable, consistent oil that allows Amarasate® to disperse effectively upon contact with the gut surface).

Patented Capsule:
A world leader in healthcare, Lonza® is the team behind our clever capsule. With more than eight years of research behind the patented design, it releases at the right spot in the digestive system to make Calocurb the most effective.

All our ingredients, including the capsule are:

  • 100% plant-based
  • Vegetarian, vegan & gluten-free
  • Glyphosate free
  • Non-GMO
  • Certified Kosher
  • Free from artificial additives, flavors and sweeteners
  • Stimulant and caffeine-free
  • GRAS (Generally Recognized As Safe) approved
Ingredients

Extraction technology

We ensure that Amarasate® is gently extracted from its unique hop flower and uses no harsh chemicals. Such a pure extraction process is known as CO2 supercritical extraction. This technology ensures we get only a 'purified hops extract' and no hop waste.

CO2 supercritical extraction removes almost all organic material from the hops, including prenylflavonoids, which research has shown to elicit a sedative effect. The prenylflavonoids are reduced to negligible levels during the production of Amarasate®.

Our hops are grown by New Zealand Hops – and we are proud to trace every batch of Calocurb back to the hops farm and farmer so you can have total transparency about their clean origin.

Extraction technology

How to take Calocurb

Your starting guide.

Day 1 - 2: Take one capsule one hour before a meal.

Day 3 - 4: Take one capsule twice daily, one hour before meals.

Day 5+: Take two capsules twice daily, one hour before meals.

Max: Four capsules daily.

Best results when taken on an empty stomach, one hour before meals. The effects of Calocurb can last up to six hours after taking a capsule.

You can tailor your dosage daily, to take between 1-4 capsules.

How to take Calocurb